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Search Result

Search Results for " corticotropin-releasing factor "

Targets

CRFR

52

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TP1144L Corticotropin-releasing factor (human) acetate Corticotropin-releasing factor (human) acetate (86784-80-7 Free base) CRFR
Corticotropin-releasing factor (human) acetate stimulates to synthesize and secret adrenocorticotropin in the anterior pituitary.
T37111 Corticotropin-releasing factor (human) (acetate)
Human CRF acetate is a chemical compound that effectively stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.
TP1144 Corticotropin-releasing factor (human) Human corticotropin-releasing factor,Human CRF,Corticotropin-releasing factor human
Corticotropin-releasing factor human (Human CRF; Human corticotropin-releasing factor) is an immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous syst...
T4329 CP 376395 CP-316311 CRFR
CP 376395 (CP-316311) is an effective and specific Corticotropin-releasing factor 1 (CRF1) receptor antagonist.
T83484 [Tyr0] Corticotropin Releasing Factor, ovine
[Tyr^0] Corticotropin Releasing Factor, ovine, is a hypothalamic hormone sourced from sheep that prompts the secretion of adrenocorticotropic hormone (ACTH) and β-endorphin [1] [2].
TP1191 CRF, bovine Corticotropin Releasing Factor bovine
CRF, bovine is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.
T76361 [DPro5] Corticotropin Releasing Factor, human, rat
[DPro5] Corticotropin Releasing Factor, human, rat, a selective R2 agonist of corticotropin-releasing factor/hormone (CRF), is a hypothalamic hormone that prompts the release of adrenocorticotropic hormone (ACTH) and β-e...
T76204 A-Helical Corticotropin Releasing Factor (9-41)
α-Helical Corticotropin Releasing Factor (9-41) is a corticotropin releasing factor (CRF) antagonist that lowers plasma growth hormone (GH) levels in vivo [1] [2].
T76360 A-Helical Corticotropin Releasing Factor (12-41)
α-Helical Corticotropin Releasing Factor (12-41), a 30-amino-acid α-helical analogue of corticotropin releasing factor/hormone (CRF), is a hypothalamic hormone that promotes adrenocorticotrophic hormone (ACTH) secretion....
T76362 [Met(O)21] Corticotropin Releasing Factor, ovine
Corticotropin Releasing Factor, ovine [Met(O)21], is a hypothalamic hormone isolated from ovine hypothalamic extracts. It functions by stimulating the secretion of adrenocorticotrophic hormone (ACTH) [1].
T83665 α-Helical CRF (9-41) TFA α-Helical Corticotropin-Releasing Factor (9-41)
α-Helical CRF (9-41) is a synthetic peptide antagonist that targets corticotropin-releasing factor (CRF), effectively inhibiting CRF-induced adrenocorticotropic hormone (ACTH) release both in vitro, with isolated rat ant...
T12492 Pivagabine CXB-722 GABA Receptor
Pivagabine (CXB-722), a hydrophobic 4-aminobutyric acid derivative, exhibits neuromodulatory activity and successfully penetrates the blood-brain barrier in rats. It counteracts the impact of foot shock on GABAA receptor...
TP1190 CRF, bovine TFA (92307-52-3 free base) CRF, bovine TFA,Corticotropin Releasing Factor bovine TFA
CRF, bovine (TFA) is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.CRF, bovine is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM[1]. CR...
T7361 Verucerfont NBI77860,GSK561679 CRFR
Verucerfont (NBI77860) is an antagonist of corticotropin-releasing factor receptor 1 (CRF1) .
TP1021 Urocortin, human Urocortin (human),Human urocortin,Human urocortin 1,Human urocortin I CRFR
Urocortin, human (Human urocortin I) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF).
T31095 Crinecerfont SSR125543,SSR 125543,SSR-125543,SSR125543A,SSR 125543A,SSR-125543A CRFR
Crinecerfont (SSR-125543) is a selective antagonist of corticotropin-releasing factor 1 receptor (CRF1) and can be used in studies about Classic congenital adrenal hyperplasia.
T16475 Pexacerfont BMS-562086 CRFR
Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).
T22577 Antalarmin hydrochloride CRFR , Immunology/Inflammation related
Antalarmin hydrochloride is an antagonist of corticotropin-releasing factor 1(CRF1). Antalarmin hydrochloride produces anti-inflammatory effects and suppresses stress-induced gastric ulceration related to irritable bowel...
TP1448L Astressin acetate Astressin acetate (170809-51-5 Free base) CRFR
Astressin acetate is an antagonist of corticotropin releasing factor (CRF) with low affinity for the CRF binding protein and high affinity for the cloned pituitary receptor(Ki = 2 nM).
TP2047L CRF (6-33) acetate(120066-38-8 free base) CRFR
CRF (6-33) acetate is a corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide; displaces CRF from CRFBP. Suppresses body weight gain and increases motor activity in obese rats in vivo.
T9857 Vasopressin antidiuretic hormone (ADH),argipressin,arginine vasopressin (AVP) Endogenous Metabolite
Vasopressin (argipressin), a cyclic nine-peptide synthesized by hypothalamic neurons, is one of the hormones involved in peptide prohormone synthesis. Vasopressin is involved in the regulation process of hypothalamic-pit...
T27227 E2508 E 2508,E-2508
E2508 is a selective antagonist of corticotropin-releasing factor 1 receptor.
T15214 Emicerfont GW876008 Others
Emicerfont is an antagonist of the corticotropin-releasing factor type 1 receptor (IC50: 66 nM).
T26856 BMS-764459
BMS-764459 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1).
T25864 NGD9002 NGD-9002,NGD 9002
NGD9002 is a novel generation, topology 2 selective corticotropin releasing factor-1 (CRF-1) receptor antagonist agent.
T12276 NVS-CRF38 Others
NVS-CRF38 is an antagonist of corticotropin-releasing factor receptor 1 (CRF1).
T71294 BMS-763534
BMS-763534 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1).
T69248 ONO-2333
ONO-2333 is a corticotropin-releasing factor receptor antagonist, for the treatment of depression and/or anxiety disorders
T33606 NBI-30545
NBI-30545 is a potent corticotropin-releasing factor-1 antagonist with sufficient lipophilicity and water solubility for the treatment of stress disorders.
T23067 NGD 98-2 hydrochloride Others
corticotropin-releasing factor receptor 1 (CRF1) antagonist
T69374 NGD 98-2
NGD 98-2 is a new generation, topology 2 selective orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist.
TP1860 Urocortin II, human
Human urocortin (hUcn) II is a new member of the corticotropin-releasing-factor (CRF) family. It selectively binds to the CRF2 receptor.
TP2048 α-Helical CRF(9-41) α-helical CRF 9-41
Corticotropin-releasing factor receptor antagonist (Ki values are 17, 5 and 0.97 at human CRF1, rat CRF2α and mouse CRF2β receptors respectively).
T38228 R 121919 hydrochloride
High affinity corticotropin releasing factor receptor1 (CRF1) antagonist (Ki = 3.5 nM). Reduces stress-induced elevations of plasma ACTH. Anxiolytic and antidepressant in vivo. Orally bioavailable. Chen and Grigoriadis (...
TP2047 CRF(6-33)(human) CRF (6-33)
CRF(6-33)(human) is a Corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide; displaces CRF from CRFBP. Suppresses body weight gain and increases motor activity in obese rats in vivo.
T75893 CRF(6-33)(human) TFA
CRF(6-33)(human) TFA acts as a competitive inhibitor of the Corticotropin-Releasing Factor Binding Protein (CRF-BP), selectively interacting with CRF-BP without affecting post-synaptic Corticotropin-Releasing Factor rece...
TP2095 Astressin 2B
Potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist (IC50 values are 1.3 and > 500 nM for CRF2 and CRF1 respectively). Antagonizes CRF2-mediated inhibition of gastric emptying.
TP2121 Sauvagine
Corticotropin-releasing factor (CRF) receptor agonist. Ki values are 9.4, 9.9, and 3.8 nM for inhibition of 125I-[D-Tyr1]astressin binding to hCRF-R1, rCRF-R2a and mCRF-R2b respectively.
TP2125 Stressin I
Potent and selective corticotropin releasing factor receptor-1 (CRF1) agonist (Ki values are 1.5 and 224 nM for CRF1 and CRF2 receptors respectively). Increases ACTH levels and increases faecal pellet output in vivo foll...
TP1504 Urocortin III, mouse TFA (357952-10-4 free base) Urocortin III, mouse TFA
Urocortin III, mouse TFA is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activates CRF-R2. Urocortin III (Ucn3) is a known component of the behavioral stress response sys...
T26855 BMS-665053 BMS665053
BMS-665053 is a corticotropin-releasing factor-1 (CRF1) receptor antagonist (IC50 = 1.0 nM). BMS-665053)11 is a potent inhibitor of CRF-stimulated cyclic adenosine monophosphate (cAMP) production in human Y-79 retinoblas...
T76602 (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a corticotropin-releasing factor (CRF) antagonist known to counteract the inhibitory effects of IL-1a on Luteinizing hormone (LH) production [1].
TP1557 Urocortin II, human TFA
Human urocortin (hUcn) II is a new member of the corticotropin-releasing-factor (CRF) family. It selectively binds to the CRF2 receptor. Human urocortin II exhibits mild motor-suppressive effects and delayed anxiolytic-l...
T76510 [Asu1,6-Arg8]Vasopressin
[Asu1,6-Arg8]Vasopressin is a vasopressin agonist that enhances cyclic AMP accumulation and adrenocorticotropic hormone (ACTH) release triggered by corticotropin-releasing factor (CRF) in cultured rat anterior pituitary ...
T76492 (Tyr0)-Urocortin, rat
(Tyr0)-Urocortin, rat, serves as a high-affinity agonist for both corticotropin-releasing factor receptor type 1 (CRF-R1) and type 2 (CRF-R2), demonstrating inhibitory binding constants (Ki) of 1-2 nM [1].
TP2091 Antisauvagine-30
Potent, selective and competitive corticotropin-releasing factor CRF2 receptor antagonist (Kd values are 1.4 and 153.6 nM for binding to mouse CRF2β and rat CRF1 receptors respectively). Inhibits sauvagine-stimulated cAM...
T36373 Urocortin II (mouse) (trifluoroacetate salt)
Urocortin II is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin III , frog sauvagine, and piscine urotensin I.1 Mouse urocortin II...
T35814 Urocortin III (human) (trifluoroacetate salt)
Urocortin III is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin II , frog sauvagine, and piscine urotensin I.1 Human urocortin II...
T76025 Urocortin III, mouse TFA
Urocortin III, mouse TFA, a corticotropin-releasing factor (CRF)-related peptide, preferentially activates CRF-R2 [1], demonstrating its significant role in the behavioral stress response system as a component of Urocort...
T76180 Urocortin III (human)
Urocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide that primarily interacts with and activates the CRF receptor type 2 (CRF-R2), showing a specific distribution in the central nervous system ...

Compounds

Corticotropin-releasing factor (human) acetate
TP1144L
Synonym: Corticotropin-releasing factor (human) acetate (86784-80-7 Free base)
Target: CRFR
Corticotropin-releasing factor (human) (acetate)
T37111
Synonym:
Target:
Corticotropin-releasing factor (human)
TP1144
Synonym: Human corticotropin-releasing factor,Human CRF,Corticotropin-releasing factor human
Target:
CP 376395
T4329
Synonym: CP-316311
Target: CRFR
[Tyr0] Corticotropin Releasing Factor, ovine
T83484
Synonym:
Target:
CRF, bovine
TP1191
Synonym: Corticotropin Releasing Factor bovine
Target:
[DPro5] Corticotropin Releasing Factor, human, rat
T76361
Synonym:
Target:
a-Helical Corticotropin Releasing Factor (9-41)
T76204
Synonym:
Target:
a-Helical Corticotropin Releasing Factor (12-41)
T76360
Synonym:
Target:
[Met(O)21] Corticotropin Releasing Factor, ovine
T76362
Synonym:
Target:
α-Helical CRF (9-41) TFA
T83665
Synonym: α-Helical Corticotropin-Releasing Factor (9-41)
Target:
Pivagabine
T12492
Synonym: CXB-722
Target: GABA Receptor
CRF, bovine TFA (92307-52-3 free base)
TP1190
Synonym: CRF, bovine TFA,Corticotropin Releasing Factor bovine TFA
Target:
Verucerfont
T7361
Synonym: NBI77860,GSK561679
Target: CRFR
Urocortin, human
TP1021
Synonym: Urocortin (human),Human urocortin,Human urocortin 1,Human urocortin I
Target: CRFR
Crinecerfont
T31095
Synonym: SSR125543,SSR 125543,SSR-125543,SSR125543A,SSR 125543A,SSR-125543A
Target: CRFR
Pexacerfont
T16475
Synonym: BMS-562086
Target: CRFR
Antalarmin hydrochloride
T22577
Synonym:
Target: CRFR, Immunology/Inflammation related
Astressin acetate
TP1448L
Synonym: Astressin acetate (170809-51-5 Free base)
Target: CRFR
CRF (6-33) acetate(120066-38-8 free base)
TP2047L
Synonym:
Target: CRFR
Vasopressin
T9857
Synonym: antidiuretic hormone (ADH),argipressin,arginine vasopressin (AVP)
Target: Endogenous Metabolite
E2508
T27227
Synonym: E 2508,E-2508
Target:
Emicerfont
T15214
Synonym: GW876008
Target: Others
BMS-764459
T26856
Synonym:
Target:
NGD9002
T25864
Synonym: NGD-9002,NGD 9002
Target:
NVS-CRF38
T12276
Synonym:
Target: Others
BMS-763534
T71294
Synonym:
Target:
ONO-2333
T69248
Synonym:
Target:
NBI-30545
T33606
Synonym:
Target:
NGD 98-2 hydrochloride
T23067
Synonym:
Target: Others
NGD 98-2
T69374
Synonym:
Target:
Urocortin II, human
TP1860
Synonym:
Target:
α-Helical CRF(9-41)
TP2048
Synonym: α-helical CRF 9-41
Target:
R 121919 hydrochloride
T38228
Synonym:
Target:
CRF(6-33)(human)
TP2047
Synonym: CRF (6-33)
Target:
CRF(6-33)(human) TFA
T75893
Synonym:
Target:
Astressin 2B
TP2095
Synonym:
Target:
Sauvagine
TP2121
Synonym:
Target:
Stressin I
TP2125
Synonym:
Target:
Urocortin III, mouse TFA (357952-10-4 free base)
TP1504
Synonym: Urocortin III, mouse TFA
Target:
BMS-665053
T26855
Synonym: BMS665053
Target:
(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
T76602
Synonym:
Target:
Urocortin II, human TFA
TP1557
Synonym:
Target:
[Asu1,6-Arg8]Vasopressin
T76510
Synonym:
Target:
(Tyr0)-Urocortin, rat
T76492
Synonym:
Target:
Antisauvagine-30
TP2091
Synonym:
Target:
Urocortin II (mouse) (trifluoroacetate salt)
T36373
Synonym:
Target:
Urocortin III (human) (trifluoroacetate salt)
T35814
Synonym:
Target:
Urocortin III, mouse TFA
T76025
Synonym:
Target:
Urocortin III (human)
T76180
Synonym:
Target:
1 2

Recombinant Proteins

Species：
Human (2)
Mouse (1)
Expression System：
E. coli (2)
HEK293 Cells (1)
Tag：
C-6xHis (1)
C-His (1)
N-6xHis-KSI (1)
Cat No. Product Name Species Expression System
TMPH-02608 Corticoliberin Protein, Mouse, Recombinant (His & KSI) Mouse E. coli
Hormone regulating the release of corticotropin from pituitary gland. Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile.
TMPJ-00906 CRHBP Protein, Human, Recombinant (His) Human HEK293 Cells
Corticotropin-Releasing Factor-Binding Protein (CRHBP) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex. The molecule is approximately 300 amino acids in length and de...
TMPY-06836 NR3C1 Protein, Human, Recombinant (His) Human E. coli
NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) is a Protein Coding gene. This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements ...
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